2001 MINNESOTA WORKSHOPS
fMRI TRAINING COURSE
OCTOBER 9-10, 2001
TUESDAY OCTOBER 9, 2001 8:00 AM – 5:00 PM
8:00 - 8:30 Registration
Introductory Lectures
8:30 - 10:00 Physiology and Mechanisms of fMRI - Kamil Ugurbil
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Basics of MR imaging
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T2, T2*, and T1 contrast in fMRI
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Neural activity vs. fMRI
10:00 - 10:30 - Coffee Break and Informal Discussion
10:30 - 12:00 MRI Sequences - Xiaoping Hu
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Basic physics of EPI
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Partial k-space sampling
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Multi-slice and 3-D Approaches
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Distortions and Field inhomogeneity, Shimming
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High Resolution Imaging with T2*- and T2-BOLD and Perfusion
12:00 - 1:00 - Lunch at the CMRR
1:00 - 2:00 Experimental Designs - Seong-Gi Kim
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Typical fMRI experimental setups including
Stimulus delivery, Behavioral and physiological data collection, Gross
head motion monitoring
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Paradigm designs including block and single-trial (event-related) fMRI
2:00 - 5:00 Hands On Data Acquisition
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4T and 7T fMRI experimental setups (2:00 - 3:30) Two sessions on each instrument.
Two groups.
7T (Amir Shmuel, Essa Yacoub)-surface coil set up. Visual situmulation,
bite bar. Go through entire set up.Physiological monitoring, monitoring
task performance
4T (Xiao-Hong Zhu, Eric Cohen) Volume coil set up. Stimulation presentation,
Physiological monitoring, monitoring task performance)
synchronization of MRI data collection and paradigm presentation
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fMRI Data Collection at 4T (Xiao-Hong Zhu, Eric Cohen, Seong-Gi Kim)
Perfusion Contrast, BOLD fMRI, Perfusion-based fMRI
Paradigm: Joystick-based Motor Task
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fMRI Data Collection at 7T (Essa Yacoub, Amir Shmuel, Xiaoping Hu)
High Resolution BOLD fMRI of visual stimulation
WEDNESDAY OCTOBER 10, 2001 8:00 AM – 4:00 PM
Data Analysis
8:00 - 9:30 Basic Principles - Wayne King
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Parametric tests: t-tests and cross-correlation
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Bonferroni Correction and clusters
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General Linear Model
9:30 - 10:00 Normalization to Standard Coordinates - John
Strupp
10:00 - 10:15 - Break
10:15 - 11:15 Preprocessing of fMRI images for Removal of Artifacts-
Xiaoping Hu
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Respiration and Cardiac
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Subject Motion
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Image Distortion
11:15 - 12:00 Overview of Other Approaches - Steve LaConte
12:00 - 1:00 - Lunch
1:00 - 4:00 Demos and Hands On Data Analysis
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Stimulate Introduction (John Strupp)
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Hands on in three groups (Eric Cohen, Xiao-Hong Zhu, Essa Yacoub)
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Break
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General Linear Model (Amir Shmuel)
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PhysioFix and DORK (Pierre-Francois van de Moortele)